Antimicrobial Case Study

AntimicrobialCase Study

AntimicrobialCase Study

Prescriptionof Beta-Lactam Antibiotic

Tony Giardano could have suffered the effects of the cat bite. Thebacteria transmitted through a cat bite is Streptococcus aureus andother Streptococcus species. Prescription of Augmentin is essentialin helping address the problem (Ellis, &amp Ellis, 2014). The drugis particularly active against the bacteria that is resistant. Thedrug falls under a class of antibiotics called the penicillinase.They are active against the bacteria that are resistant topenicillin.

RecommendedDose

Children older than five years old are given 875 mg PO q12hr or 500mg PO q8hr for 3-5 days (Bru &amp Garraffo, 2012). Tony can begiven the dosage to help address the problem.

DrugAction and Use

Augmentin employs the same mode of action as the penicillin drugs. Itinterferes with the final stage of the bacterial cell wall synthesis.The drug binds the penicillin-binding proteins preventing thecross-linking that is required to form a stable bacterial cell wall(Cho, Uehara, &amp Bernhardt, 2014). The effect is autolysis thatresults from the autolysins. The bacterial cell wall is essential inthe microorganism. It maintains the integrity of the cellularcomponents of the bacteria. The inability to uphold such integrityinterferes with the cellular activities within the microorganismresulting in the death of the bacteria. The patient is likely torecover from the effects of the bacteria.

ClinicalDrug Dosing

The dose administered for the drug varies depending on the patientand the severity of the condition. Further, it is essential toconsider Tony’s response. For the patient, the administration ofthe drug should take place for at least fourteen days, but the samecan be extended for up to four weeks depending on his response.Clinical dosing should be in line with the recommendations of theWorld Health Organization.

References

Ellis, R., &amp Ellis, C. (2014). Dog and cat bites. Americanfamily physician, 90(4).

Cho, H., Uehara, T., &amp Bernhardt, T. G. (2014). Beta-lactamantibiotics induce a lethal malfunctioning of the bacterial cell wallsynthesis machinery. Cell, 159(6), 1310–1311.http://doi.org/10.1016/j.cell.2014.11.017